@misc{10481/54463,
year = {2018},
month = {4},
url = {http://hdl.handle.net/10481/54463},
abstract = {Objectives
To examine the association of objectively measured physical activity (PA) intensity
levels and sedentary time with arterial stiffness in women with systemic lupus erythematosus
(SLE) with mild disease activity and to analyze whether participants meeting the
international PA guidelines have lower arterial stiffness than those not meeting the PA
guidelines.
Methods
The study comprised 47 women with SLE (average age 41.2 [standard deviation 13.9])
years, with clinical and treatment stability during the 6 months prior to the study. PA intensity
levels and sedentary time were objectively measured with triaxial accelerometry. Arterial
stiffness was assessed through pulse wave velocity, evaluated by Mobil-O-Graph® 24h
pulse wave analysis monitor.
Results
The average time in moderate to vigorous PA in bouts of  10 consecutive minutes was
135.1±151.8 minutes per week. There was no association of PA intensity levels and sedentary
time with arterial stiffness, either in crude analyses or after adjusting for potential confounders. Participants who met the international PA guidelines did not show lower pulse
wave velocity than those not meeting them (b = -0.169; 95% CI: -0.480 to 0.143; P = 0.280).
Conclusions
Our results suggest that PA intensity levels and sedentary time are not associated with arterial
stiffness in patients with SLE. Further analyses revealed that patients with SLE meeting
international PA guidelines did not present lower arterial stiffness than those not meeting
the PA guidelines. Future prospective research is needed to better understand the association
of PA and sedentary time with arterial stiffness in patients with SLE.},
organization = {This work was supported by Fundación
para la Investigación Biosanitaria de Andalucia
Oriental, Grant numbers: PI-0525-2016 (http://
www.fibao.es/; http://www.ibsgranada.es/) to
JAVH. The funder had no role in study design, data collection and analysis, decision to publish, or
preparation of the manuscript.},
publisher = {Xu-jie Zhou, Peking University First Hospital, CHINA},
title = {Association of objectively measured physical activity and sedentary time with arterial stiffness in women with systemic lupus erythematosus with mild disease activity},
doi = {e0196111},
author = {Morillas de Laguno, Pablo and Vargas-Hitos, José Antonio and Rosales-Castillo, Antonio and Sáez Urán, Luis Manuel and Montalbán-Méndez, Cristina and Gavilán Carrera, Blanca and Navarro-Mateos, Carmen and Acosta Manzano, Pedro and Delgado Fernández, Manuel and M. Sabio, José and Ortego-Centeno, Norberto and Callejas Rubio, José Luis and Soriano‑Maldonado, Alberto},
}