@misc{10481/53242,
year = {2018},
month = {2},
url = {http://hdl.handle.net/10481/53242},
abstract = {Objectives: Biomaterials for treating dentin hypersensitivity and dentin wear were
evaluated, to efficiently occlude the dentinal tubules and to increase dentin resistance to
abrasion. Materials and Methods: 24 dentin surfaces were treated with EDTA to expose
dentinal tubules, and were: 1) non-brushed, 2) brushed with distilled water, or with pastes
containing 3) Monetite, 4) Brushite, 5) Zn-Monetite, 6) Zn-Brushite, 7) Silica-Brushite
and 8) NovaMin®. Topography, nanomechanical and chemical analysis were assessed on
dentin surfaces (n=3) after artificial saliva immersion for 24 h, and after citric acid
challenge. 21 further dentin specimens were created to evaluate dentin permeability after
brushing, saliva storage and acid application (n=3). ANOVA, Student-Newman-Keuls
(p<0.05) and Student t-test (p<0.001) were used. Results: Particles containing major
proportion of silica attained intratubular occlusion by carbonate crystals (Raman
carbonate peak heights: 15.17 and 19.24 au; complex modulus: 110 and 140 GPa, at
intratubular dentin). When brushing with pastes containing higher proportion of silica or
zinc, phosphate calcium compounds were encountered into tubules and over dentin
surfaces (Raman intratubular phosphate peak heights: 49 to 70 au, and at the intertubular
dentin: 78 to 92). The formed carbonated apatite and calcium phosphate layer were
resistant to citric acid application. Zinc compounds drastically increased tubule occlusion,
decreased dentin permeability (up to 30%) and augmented mechanical properties at the
intertubular dentin (90-130 GPa), it was maintained after acid challenging. Conclusions:
Zinc-containing pastes occluded dentinal tubules and improved dentin mechanical
properties. Clinical Relevance: Using zinc as an active component to treat eroded dentin
is encouraged.},
organization = {Projects RTC-2014-1731-1 and MAT2014-52036-P
supported by the Ministry of Economy and Competitiveness and European Regional
Development Fund.},
keywords = {Zinc},
keywords = {Silica},
keywords = {dentin},
keywords = {mechanical properties},
keywords = {Raman},
title = {Zinc and silica are active components to efficiently treat in vitro simulated eroded dentin.},
doi = {10.1007/s00784-018-2372-7},
author = {Osorio Ruiz, Raquel and Toledano Osorio, Manuel and Osorio Ruiz, María Estrella and Sánchez Aguilera, Fátima and Padilla-Mondéjar, Sussette and Toledano Pérez, Manuel},
}