@misc{10481/28987, year = {2009}, url = {http://hdl.handle.net/10481/28987}, abstract = {OBJECTIVE: To examine the relationship between birth weight and abdominal adiposity in adolescents. RESEARCH DESIGN AND METHODS: A total of 284 adolescents (49.3% of whom were female) aged 14.9 +/- 1.2 years were included in the study. Birth weight and gestational age were obtained from parental records. Abdominal adiposity (in three regions: R1, R2, and R3) and trunk and total body fat mass were measured by dual-energy X-ray absorptiometry. Regional fat mass indexes (FMIs) were thereafter calculated as fat mass divided by the square of height (Trunk FMI and abdominal FMI R1, R2, and R3). RESULTS: Birth weight was negatively associated with abdominal FMI R1, R2, and R3 independently of total fat mass, gestational age, sex, breast-feeding duration, pubertal stage, physical activity, and socioeconomic status (all P < 0.01). CONCLUSIONS: Our study shows an inverse association between birth weight and abdominal adiposity in adolescents independently of total fat mass and other potential confounders. These findings suggest that fetal nutrition, as reflected by birth weight, may have a programming effect on abdominal adiposity later in life.}, organization = {The HELENA study was carried out with the financial support of the European Community Sixth RTD Framework Programme (contract no. FOOD-CT-2005-007034). This work was also partially supported by the Swedish Council for Working Life and Social Research (to F.A.S.), the Spanish Ministry of Education (EX-2007-1124), and the Spanish Ministry of Health: Maternal, Child Health and Development Network (RD08/ 0072).}, publisher = {American Diabetes Association}, keywords = {Abdominal fat}, keywords = {Absorptiometry}, keywords = {Adolescent}, keywords = {Birth weight}, keywords = {Cardiovascular diseases}, keywords = {Risk factors}, keywords = {Spain}, title = {Early life programming of abdominal adiposity in adolescents: The HELENA Study}, author = {Labayen, Idoia and Ruiz Ruiz, Jonatan and Vicente-Rodríguez, Germán and Turck, Dominique and Rodríguez, G. and Meirhaeghe, Aline and Molnar, Dénes and Sjöström, Michael and Castillo Garzón, Manuel J. and Gottrand, Frederic and Moreno, L. A.}, }