TY - JOUR AU - Risso, Valeria Alejandra AU - Gavira Gallardo, José Antonio AU - Gaucher, Eric A. AU - Mejia-Carmona, DF AU - Sánchez Ruiz, José Manuel PY - 2013 UR - https://hdl.handle.net/10481/87028 AB - We report a sequence reconstruction analysis targeting several Precambrian nodes in the evolution of class-A β-lactamases and the preparation and experimental characterization of their encoded proteins. Despite extensive sequence differences with the... LA - eng PB - AMER CHEMICAL SOC TI - Hyperstability and substrate promiscuity in laboratory resurrections of precambrian β-lactamases T2 - JACS DO - 10.1021/ja311630a ER -