TY - JOUR AU - Mariotto, Elena AU - Giampietro, Viola AU - Ronca, Roberto AU - Persano, Luca AU - Aveic, Sanja AU - Bhujwalla, Zaver M. AU - Mori, Noriko AU - Accordi, Benedetta AU - Serafin, Valentina AU - López Cara, Luisa Carlota AU - Bortolozzi, Roberta PY - 2018 SN - 2072-6694 UR - http://hdl.handle.net/10481/55589 AB - Choline kinase (ChoK) is the first enzyme of the Kennedy pathway leading to the biosynthesis of phosphatidylcholine (PtdCho), the most abundant phospholipid in eukaryotic cell membranes. EB-3D is a novel choline kinase 1 (ChoK 1) inhibitor with... LA - eng PB - MDPI KW - Choline Kinase α KW - Breast cancer KW - Small molecules KW - Senescence TI - Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer ER -