TY  - JOUR 
AU  - González Cantero, Jorge
AU  - Martín Rodríguez, José Luis
AU  - González Cantero, Álvaro
AU  - Arrebola Moreno, Juan Pedro
AU  - González Calvín, Jorge Luis
PY  - 2018
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/49757
AB  - Insulin resistance is the pathophysiological precursor of type 2 diabetes mellitus (DM-2), and its relationship with non-alcoholic fatty liver disease (NAFLD) has been widely studied in patients with obesity or metabolic syndrome using not only...
AB  - A cross-sectional study was conducted in 113 non-obese, non-diabetic individuals classified as overweight (BMI 25–29.9 kg/m2) or lean (BMI 19.5–24.9 kg/m2). Hepatic triglyceride content was quantified by 3T H1-MRS. NAFLD was defined as hepatic...
AB  - HOMA-IR was significantly correlated with hepatic triglyceride content (r:0.76; p<0.0001). The lean-with-NAFLD group had significantly higher HOMA-IR (p<0.001) and lower serum adiponectin (p<0.05) than the overweight-without-NAFLD group. Insulin...
AB  - Our findings suggest that NAFLD, once established, seems to be involved in insulin resistance and cardio-metabolic risk factors above and beyond waist circumference and BMI in non-obese, non-diabetic Caucasian individuals.
LA  - eng
PB  - Public Library of Science
KW  - Insulin resistance
KW  - Fatty liver
KW  - Adiponectin
KW  - Body mass index
KW  - Fats
KW  - Aminotransferases
KW  - Cholesterol
KW  - Regression analysis
TI  - Insulin resistance in lean and overweight non-diabetic Caucasian adults: Study of its relationship with liver triglyceride content, waist circumference and BMI
DO  - 10.1371/journal.pone.0192663
ER  -