TY  - JOUR 
AU  - Torres-Espínola, Francisco J.
AU  - Berglund, Staffan K.
AU  - García-Valdés, Luz
AU  - Segura, María Teresa
AU  - Jerez, Antonio
AU  - Campos, Daniel
AU  - Moreno-Torres, Rosario
AU  - Rueda, Ricardo
AU  - Catena Martínez, Andrés
AU  - Pérez García, Miguel
AU  - Campoy Folgoso, Cristina
AU  - Grupo PREOBE
PY  - 2015
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/37841
AB  - Background:

Brain development in fetal life and early infancy is critical to determine lifelong performance in various neuropsychological domains. Metabolic pathologies such as overweight, obesity, and gestational diabetes in pregnant women are...
AB  - Objective:

The objective of this research was to investigate the influence of maternal metabolic pathologies on the neurodevelopment of the offspring at 6 and 18 months of life.
AB  - Design:

This was a prospective case-control study of 331 mother- and child pairs from Granada, Spain. The mothers were included during pregnancy into four groups according to their pre-gestational body mass index and their gestational diabetes...
AB  - Results:

At 6 months (n=215), we found significant group differences in cognition composite language, and expressive language. Post hoc test revealed unexpectedly higher scores in the obese group compared to the normal weight group and a similar...
AB  - Conclusions:

Infants of obese mothers had a temporary accelerated development of cognition and language, followed by a rapid deceleration until 18 months of age, particularly of language scores. This novel observation prompts further confirmative...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Gestational diabetes
KW  - Language
KW  - Obesity
KW  - Childhood obesity
KW  - Pregnancy
KW  - Infants
KW  - Neurodevelopment
KW  - Diabetes mellitus
TI  - Maternal Obesity, Overweight and Gestational Diabetes Affect the Offspring Neurodevelopment at 6 and 18 Months of Age – A Follow Up from the PREOBE Cohort
DO  - 10.1371/journal.pone.0133010
ER  -