TY  - JOUR 
AU  - Pineda de las Infantas y Villatoro, María J.
AU  - Unciti-Broceta, Juan Diego
AU  - Contreras-Montoya, Rafael
AU  - García-Salcedo, José Antonio
AU  - Gallo Mezo, Miguel Ángel
AU  - Unciti-Broceta, Asier
AU  - Díaz Mochón, Juan José
PY  - 2015
SN  - 2045-2322
UR  - http://hdl.handle.net/10481/35509
AB  - Anovel one-pot synthesis of tri-substituted purines and the discovery of purine analogues with trypanocidal activity are reported. The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and diaminopyrimidines with Schiff...
LA  - eng
PB  - Nature Publishing Group
KW  - Reaction mechanisms
KW  - Parasite biology
KW  - Purines
KW  - Trypanosoma brucei
KW  - Trypanocidal activity
TI  - Amide-controlled, one-pot synthesis of tri-substituted purines generates structural diversity and analogues with trypanocidal activity
DO  - 10.1038/srep09139
ER  -