TY - JOUR AU - Iglesias-Bexiga, Manuel AU - Castillo, Francisco AU - Sánchez Cobos, Eva María AU - Oka, Tsutomu AU - Sudol, Marius AU - Luque Fernández, Irene PY - 2015 SN - 1932-6203 UR - http://hdl.handle.net/10481/34873 AB - YAP is a WW domain-containing effector of the Hippo tumor suppressor pathway, and the object of heightened interest as a potent oncogene and stemness factor. YAP has two major isoforms that differ in the number of WW domains they harbor. Elucidating... LA - eng PB - Public Library of Science (PLOS) KW - Sequence motif analysis KW - Protein domains KW - Binding analysis KW - Cell binding KW - Peptides KW - Calorimetry KW - Thermodynamics KW - Electrostatic bonding TI - WW Domains of the Yes-Kinase-Associated-Protein (YAP) Transcriptional Regulator Behave as Independent Units with Different Binding Preferences for PPxY Motif-Containing Ligands DO - 10.1371/journal.pone.0113828 ER -