TY  - JOUR 
AU  - Bacarizo, Julio
AU  - Martínez Rodríguez, Sergio
AU  - Martín-García, José Manuel
AU  - Andújar-Sánchez, Montserrat
AU  - Ortiz-Salmerón, Emilia
AU  - Neira, José Luis
AU  - Cámara-Artigas, Ana
PY  - 2014
SN  - 1932-6203
UR  - http://hdl.handle.net/10481/34836
AB  - The SH3 domain of the c-Src tyrosine kinase (c-Src-SH3) aggregates to form intertwined dimers and amyloid fibrils at mild acid pHs. In this work, we show that a single mutation of residue Gln128 of this SH3 domain has a significant effect on: (i) its...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Crystal structure
KW  - Molecular structure
KW  - Protein structure
KW  - Tyrosine
KW  - Oligomers
KW  - Nucleation
KW  - Fluorescence
KW  - Protein domains
TI  - Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation
DO  - 10.1371/journal.pone.0113224
ER  -