TY - JOUR AU - Majtan, Tomas AU - Pey Rodríguez, Ángel Luis AU - Fernández, Roberto AU - Fernández, José A. AU - Martínez-Cruz, Luis A. AU - Kraus, Jan P. PY - 2014 SN - 1932-6203 UR - http://hdl.handle.net/10481/32857 AB - Cystathionine beta-synthase (CBS) is a key regulator of sulfur amino acid metabolism diverting homocysteine, a toxic intermediate of the methionine cycle, via the transsulfuration pathway to the biosynthesis of cysteine. Although the pathway itself is... LA - eng PB - Public Library of Science (PLOS) KW - Cofactors (biochemistry) KW - Crystal structure KW - Enzyme purification KW - Enzyme regulation KW - Enzymes KW - Heme KW - Matrix-assisted laser desoprtion ionization mass spectrometry KW - Polymerase chain reaction TI - Domain Organization, Catalysis and Regulation of Eukaryotic Cystathionine Beta-Synthases DO - 10.1371/journal.pone.0105290 ER -