TY  - JOUR 
AU  - Sebastiani, Paola
AU  - Abad Grau, María Del Mar
PY  - 2007
SN  - 1471-2156
UR  - http://hdl.handle.net/10481/31189
AB  - [Background]

The maximum likelihood estimator of D' – a standard measure of linkage disequilibrium – is biased toward disequilibrium, and the bias is particularly evident in small samples and rare haplotypes.
[Results]

This paper proposes a...
LA  - eng
PB  - Biomed Central
KW  - Bayes theorem
KW  - Haplotypes
KW  - Human genome project
KW  - Humans
KW  - Likelihood functions
KW  - Linkage disequilibrium
KW  - Models
KW  - Genetic
KW  - Polymorphism
KW  - Single nucleotide
TI  - Bayesian estimates of linkage disequilibrium
ER  -