TY - JOUR AU - Calvanese, Vicenzo AU - Horrillo, Angelica AU - Hmadcha, Abdelkrim AU - Suárez-Álvarez, Beatriz AU - Fernández, Agustín F. AU - Lara, Ester AU - Casado, Sara AU - Menéndez, Pablo AU - Bueno, Clara AU - García-Castro, Javier AU - Rubio, Ruth AU - Lapunzina, Pablo AU - Alaminos Mingorance, Miguel AU - Borghese, Lodovica AU - Terstegge, Stefanie AU - Harrison, Neil J. AU - Moore, Harry D. AU - Brüstle, Oliver AU - López Larrea, Carlos AU - Andrews, Peter W. AU - Soria, Bernat AU - Esteller, Manel AU - Fraga, Mario F. PY - 2008 SN - 1932-6203 UR - http://hdl.handle.net/10481/30782 AB - Developmental genes are silenced in embryonic stem cells by a bivalent histone-based chromatin mark. It has been proposed that this mark also confers a predisposition to aberrant DNA promoter hypermethylation of tumor suppressor genes (TSGs) in... LA - eng PB - Public Library of Science (PLOS) KW - Cell differentiation KW - DNA KW - Embryonic stem cells KW - Lymphocytes KW - Neutrophils KW - Stem cells TI - Cancer genes hypermethylated in human embryonic stem cells ER -