TY - JOUR AU - Bullón, Pedro AU - Battino, Maurizio AU - Varela López, Alfonso AU - Pérez-López, Patricia AU - Granados Principal, Sergio AU - Ramírez Tortosa, María Carmen AU - Ochoa Herrera, Julio José AU - Cordero, Mario D. AU - González-Alonso, Adrián AU - Ramírez Tortosa, César Luis AU - Rubini, Corrado AU - Zizzi, Antonio AU - Quiles Morales, José Luis PY - 2013 SN - 1932-6203 UR - http://hdl.handle.net/10481/29700 AB - Background/Objectives: Aging enhances frequency of chronic diseases like cardiovascular diseases or periodontitis. Here we reproduced an age-dependent model of the periodontium, a fully physiological approach to periodontal conditions, to evaluate... AB - Methods/Findings: Animals were fed life-long on diets based on monounsaturated fatty acids (MUFA) as virgin olive oil, n-6 polyunsaturated fatty acids (n-6PUFA), as sunflower oil, or n-3PUFA, as fish oil. Age-related alveolar bone loss was higher... AB - Conclusions: The main finding is that the enhanced alveolar bone loss associated to age may be targeted by an appropriate dietary treatment. The mechanisms involved in this phenomenon are related with an ablation of the cell capacity to adapt to... LA - eng PB - Public Library of Science (PLOS) KW - Aging KW - Alveolar bone KW - Diet KW - Fatty acids KW - Mitochondria KW - Periodontitis KW - Sunflower KW - Vegetable oils TI - Diets based on virgin olive oil or fish oil but not on sunflower oil prevent age-related alvolar bone resorption by mitochondrial-related mechanisms ER -