TY - JOUR AU - López-Abente, Gonzalo AU - García-Gómez, Montserrat AU - Menéndez Navarro, Alfredo AU - Fernández-Navarro, Pablo AU - Ramis, Rebeca AU - García-Pérez, Javier AU - Cervantes, Marta AU - Ferreras, Eva AU - Jiménez-Muñoz, María AU - Pastor-Barriuso, Roberto PY - 2013 SN - 1471-2407 UR - http://hdl.handle.net/10481/29403 AB - Background A total of 2,514,346 metric tons (Mt) of asbestos were imported into Spain from 1906 until the ban on asbestos in 2002. Our objective was to study pleural cancer mortality trends as an indicator of mesothelioma mortality and update... AB - Methods Log-linear Poisson models were fitted to study the effect of age, period of death and birth cohort (APC) on mortality trends. Change points in cohort- and period-effect curvatures were assessed using segmented regression. Fractional... AB - Results Pleural cancer deaths increased across the study period, rising from 491 in 1976–1980 to 1,249 in 2006–2010. Predictions for the five-year period 2016–2020 indicated a total of 1,319 pleural cancer deaths (264 deaths/year). Forecasts up to... AB - Conclusion The cancer mortality-related consequences of human exposure to asbestos are set to persist and remain in evidence until the last surviving members of the exposed cohorts have disappeared. It can thus be assumed that occupationally-related... LA - eng PB - Biomed Central KW - Age-period-cohort KW - Asbestos KW - Epidemiology KW - Pleural cancer KW - Mesothelioma KW - Spain TI - Pleural cancer mortality in Spain: time-trends and updating of predictions up to 2020 ER -