TY - JOUR AU - Delaye, Luis AU - González Domenech, Carmen M. AU - Garcillán-Barcia, María P. AU - Peretó, Juli AU - Cruz, Fernando de la AU - Moya, Andrés PY - 2011 SN - 1471-2164 UR - http://hdl.handle.net/10481/28224 AB - Background: Simpler biological systems should be easier to understand and to engineer towards pre-defined goals. One way to achieve biological simplicity is through genome minimization. Here we looked for genomic islands in the fresh water... AB - Results: By using a combination of methods we identified 170 xenologs, 136 ORFans and 1401 core genes in the genome of S. elongatus PCC 7942. These represent 6.5%, 5.2% and 53.6% of the annotated genes respectively. We considered that genes in... AB - Conclusions: Our estimates of genomic islands in PCC 7942 are larger than those predicted by other published methods like SIGI-HMM. Our results set a guide to non-essential genes in S. elongatus PCC 7942 indicating a path towards the engineering of a... LA - eng PB - Biomed Central KW - Bacterial proteins KW - Gene transfer KW - Genome KW - Genomic islands KW - Phylogeny KW - Synechococcus TI - Blueprint for a minimal photoautotrophic cell: conserved and variable genes in Synechococcus elongatus PCC 7942 ER -