A novel bioactive agent improves adhesion of resin-modified glass-ionomer to dentin Osorio Ruiz, María Estrella Ticiane, Fagundes Navarro, Maria Fidela Zanotto, Edgar D. Peiti, Oscar Osorio Ruiz, Raquel Toledano Osorio, Manuel Toledano Pérez, Manuel Resin-modified glass-ionomer cement Dentin Adhesion Compression Bioactive materials “This is an Accepted Manuscript of an article published by Taylor & Francis in Journal of Adhesion Science and Technology on 2015-05-05, available online: http://www.tandfonline.com/10.1080/01694243.2015.1030897.” Bioactive glasses are surface-active materials able induce remineralization of dental structure. Objectives: to evaluate the effect of doping two resin-modified glass ionomer cements (RMGICs) with a bioactive glass (Biosilicate) in compressive and microtensile bond strength (MTBS) to dentin. Methods: Experimental powders were made by incorporating 2, 5, and 10 wt% of biosilicate in Vitremer (VT) and Fuji II LC (FL) powder. FL and VT were used as control materials. Six cylinders of each experimental material were tested for failure in compression at 1.0mm/min, after 24h storage in distilled water at 37ºC. For the bond strength test, thirty non-carious human molars underwent cavity preparation previous to restoration. Restorative materials were VT or FL with and without 2 wt% biosilicate. The teeth were stored in water at 37ºC for 24h or 7d, sectioned into beams, and tested for failure in tension at 0.5 mm/min. Compressive and bond strength data were analyzed by analysis of variance and multiple-comparison tests (p<0.05). Analysis of de-bonded specimens was performed by scanning electron microscopy (SEM). Results: Only incorporation of 2 wt% of biosilicate did not decrease the compressive strength of the tested RMGICs. The incorporation of 2 wt% biosilicate into RMGICs produced and increase in bond strength after 24h for FL, and after 24h and 7d for VT. Significance: Incorporation of 2 wt% of biosilicate particles into RMGICs did not affect the compressive strength and improved bond strength to dentin.   2016-06-07T06:34:57Z 2016-06-07T06:34:57Z 2015 info:eu-repo/semantics/article Osorio, E.; et al. A novel bioactive agent improves adhesion of resin-modified glass-ionomer to dentin. Journal Adhesion Science and Technology, 29(15): 1543–1552 (2015). [http://hdl.handle.net/10481/41608] 0169-4243 1568-5616 http://hdl.handle.net/10481/41608 10.1080/01694243.2015.1030897 eng http://creativecommons.org/licenses/by-nc-nd/3.0/ info:eu-repo/semantics/openAccess Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Taylor & Francis