Conditional and Unconditional Tests (and Sample Size) Based on Multiple Comparisons for Stratified 2 × 2 Tables Martín Andrés, Antonio Herranz Tejedor, Inmaculada Álvarez Hernández, María Mantel-Haenszel test Birch test Stratified test Métodos estadísticos Dichotomic qualities Estadística médica The Mantel-Haenszel test is the most frequent asymptotic test used for analyzing stratified 2x2 tables. Its exact alternative is the test of Birch, which has recently been reconsidered by Jung. Both tests have a conditional origin: Pearson’s chi-squared test and Fisher’s exact test, respectively. But both tests have the same drawback that the result of global test (the stratified test) may not be compatible with the result of individual tests (the test for each stratum). In this paper, we propose to carry out the global test using a multiple comparisons method (MC method) which does not have this disadvantage. By refining the method (MCB method) an alternative to the Mantel-Haenszel and Birch tests may be obtained. The new MC and MCB methods have the advantage that they may be applied from an unconditional view, a methodology which until now has not been applied to this problem. We also propose some sample size calculation methods. 2015-06-24T12:04:09Z 2015-06-24T12:04:09Z 2015 info:eu-repo/semantics/article Martín Andrés, A.; Herranz Tejedor, I.; Álvarez Hernández, M. Conditional and Unconditional Tests (and Sample Size) Based on Multiple Comparisons for Stratified 2 × 2 Tables. Computational and Mathematical Methods in Medicine, 2015: 147038 (2015). [] 1748-670X 1748-6718 http://hdl.handle.net/10481/36740 10.1155/2015/147038 eng info:eu-repo/semantics/openAccess Hindawi Publishing Corporation