Comparative characterization of phenolic and other polar compounds in Spanish melon cultivars by using high-performance liquid chromatography coupled to electrospray ionization quadrupole-time of flight mass spectrometry Rodríguez Pérez, Celia Quirantes-Piné, Rosa Segura Carretero, Antonio Fernández Gutiérrez, Alberto Cucumis melo Characterization Phenolic compounds PCA Tandem mass spectrometry Melon (Cucumis melo L.), belonging to the Cucurbitaceae family, is a significant source of phytochemicals which provide human health benefits. High-performance liquid chromatography coupled to electrospray ionization mass spectrometry quadropole-time of flight (HPLC-ESIQTOF-MS) was used for the comprehensive characterization of 14 extracts from 3 Spanish varieties of melon (Galia, Cantaloupe, and Piel de Sapo). A total of 56 different compounds were tentatively identified, including: amino acids and derivatives, nucleosides, organic acids, phenolic acids and derivatives, esters, flavonoids, lignans, and other polar compounds. Of these, 25 were tentatively characterized for the first time in C. melo varieties. Principalcomponent analysis (PCA) was applied to gain an overview of the distribution of the melon varieties and to clearly separate the different varieties. The result of the PCA for the negative mode was evaluated. The variables most decisive to discriminate among varieties included 12 of the metabolites tentatively identified. 2013-10-22T08:22:33Z 2013-10-22T08:22:33Z 2013-09-15 info:eu-repo/semantics/preprint Rodríguez-Pérez, C.; et al. Comparative characterization of phenolic and other polar compounds in Spanish melon cultivars by using high-performance liquid chromatography coupled to electrospray ionization quadrupole-time of flight mass spectrometry. Food Research International (2013). [http://hdl.handle.net/10481/28512] 0963-9969 1873-7145 http://hdl.handle.net/10481/28512 10.1016/j.foodres.2013.09.011 eng http://creativecommons.org/licenses/by-nc-nd/3.0/ info:eu-repo/semantics/openAccess Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License Elsevier