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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/49192

Title: A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease
Authors: Varela-López, Alfonso
Giampieri, Francesca
Bullón, Pedro
Battino, Maurizio
Quiles Morales, José Luis
Issue Date: 7-Sep-2016
Abstract: Periodontal disease is an inflammatory disease with high prevalence in adults that leads to destruction of the teeth-supporting tissues. Periodontal therapy has been traditionally directed at reduction of the bacterial load to a level that encourages health-promoting bacteria and maintenance of oral-hygiene. The role of nutrition in different chronic inflammatory diseases has been the subject of an increasing body of research in the last decades. In this sense, there has been an important increase in the volume of research on role of nutrition in periodontitis since the diet has known effects on the immune system and inflammatory cascades. Minerals play a key role in all these processes due to the multiple pathways where they participate. To clarify the role of the different minerals in the establishment, progression and/or treatment of this pathology, a systemically review of published literature cited in PubMed until May 2016 was conducted, which included research on the relationship of these elements with the onset and progression of periodontal disease. Among all the minerals, calcium dietary intake seems important to maintain alveolar bone. Likewise, dietary proportions of minerals that may influence its metabolism also can be relevant. Lastly, some observations suggest that all those minerals with roles in immune and/or antioxidant systems should be considered in future research.
Sponsorship: Alfonso Varela-López is recipient of a “Contrato Puente” from the University of Granada. Authors acknowledge to the University of Granada and the Autonomous Government of Andalusia for partial support of the research team. Francesca Giampieri was supported by a Fondazione Umberto Veronesi Fellowship.
Publisher: MDPI
Keywords: Mineral
Oral health
URI: http://hdl.handle.net/10481/49192
ISSN: 1420-3049
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Varela-López, A.; et al. A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease. Molecules, 21(9): 1183 (2016). [http://hdl.handle.net/10481/49192]
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