Universidad de Granada Digibug
 

Repositorio Institucional de la Universidad de Granada >
1.-Investigación >
Departamentos, Grupos de Investigación e Institutos >
Departamento de Anatomía y Embriología Humana >
DAEH - Artículos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/49137

Title: Knee Viscosupplementation: Cost-Effectiveness Analysis between Stabilized Hyaluronic Acid in a Single Injection versus Five Injections of Standard Hyaluronic Acid
Authors: Estades-Rubio, Francisco J.
Reyes-Martín, Alvaro
Morales-Marcos, Víctor
García-Piriz, Mercedes
García-Vera, Juan J.
Perán Quesada, Macarena
Marchal Corrales, Juan Antonio
Montañez-Heredia, Elvira
Issue Date: 17-Mar-2017
Abstract: Given the wide difference in price per vial between various presentations of hyaluronic acid, this study seeks to compare the effectiveness and treatment cost of stabilized hyaluronic acid (NASHA) in a single injection with standard preparations of hyaluronic acid (HA) in five injections in osteoarthritis (OA) of the knee. Fifty-four patients with knee osteoarthritis (Kellgren–Lawrence Grade II and III) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain score greater than 7, with a homogeneous distribution of age, sex, BMI, and duration of disease, were included in this study. Patients were randomized into two groups: Group I was treated with NASHA (Durolane®) and Group II with HA (Go-ON®). Patient’s evolution was followed up at the 1st, 2nd, 4th, 8th, 12th, and 26th week after treatment. A statistically significant improvement in WOMAC score was observed for patients treated with NASHA versus those who received HA at Week 26. In addition, the need for analgesia was significantly reduced at Week 26 in the NASHA-treated group. Finally, the economic analysis showed an increased cost of overall treatment with HA injections. Our data support the use of the NASHA class of products in the treatment of knee OA.
Publisher: MDPI
Keywords: Knee osteoarthritis
Hyaluronic acid
Stabilized hyaluronic acid (NASHA)
URI: http://hdl.handle.net/10481/49137
ISSN: 1422-0067
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Estades-Rubio, F.J.; et al. Knee Viscosupplementation: Cost-Effectiveness Analysis between Stabilized Hyaluronic Acid in a Single Injection versus Five Injections of Standard Hyaluronic Acid. International Journal of Molecular Sciences, 18(3): 658 (2017). [http://hdl.handle.net/10481/49137]
Appears in Collections:DAEH - Artículos

Files in This Item:

File Description SizeFormat
EstadesRubio_NASHA.pdf249.47 kBAdobe PDFView/Open
Recommend this item

This item is licensed under a Creative Commons License
Creative Commons

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! OpenAire compliant DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - Feedback

© Universidad de Granada