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Oral Mucositis: Melatonin Gel an Effective New Treatment

dc.contributor.authorMoneim, Ahmed E. Abdeles_ES
dc.contributor.authorGuerra Librero Rite, Ana es_ES
dc.contributor.authorFlorido Ruiz, Javier es_ES
dc.contributor.authorShen, Ying-Qianges_ES
dc.contributor.authorFernández-Gil, Beatrizes_ES
dc.contributor.authorAcuña Castroviejo, Darío es_ES
dc.contributor.authorEscames Rosa, Germaine es_ES
dc.date.accessioned2018-01-23T10:27:49Z
dc.date.available2018-01-23T10:27:49Z
dc.date.issued2017
dc.identifier.citationMoneim, A.E.A.; et al. Oral Mucositis: Melatonin Gel an Effective New Treatment. International Journal of Molecular Sciences, 18(5): 1003 (2017). [http://hdl.handle.net/10481/49107]es_ES
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/10481/49107
dc.description.abstractThe current treatment for cervico-facial cancer involves radio and/or chemotherapy. Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause a considerably reduced quality of life in cancer patients already suffering from physical and psychological exhaustion. However, the role of melatonin in the treatment of mucositis has recently been investigated, and offers an effective alternative therapy in the prevention and/or management of radio and/or chemotherapy-induced mucositis. This review focuses on the pathobiology and management of mucositis in order to improve the quality of cancer patients’ lives.en_EN
dc.description.sponsorshipPart of this study was partially funded by the following grants: SAF2009-14037 from the Spanish Ministry of Economy and Competitivity (MINECO), CB/10/00238 from the Carlos III Health Institute, GREIB.PT_2010_04 from the CEIBiotic Program of the University of Granada, Spain, and CTS-101 from the Innovation, Science, and Business Council, Junta de Andalucía, Spain.en_EN
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es_ES
dc.subjectMucositisen_EN
dc.subjectRadiotherapy en_EN
dc.subjectChemotherapyen_EN
dc.subjectPathophysiologyen_EN
dc.subjectManagementen_EN
dc.subjectMelatoninen_EN
dc.titleOral Mucositis: Melatonin Gel an Effective New Treatmenten_EN
dc.typeinfo:eu-repo/semantics/articleen_EN
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen_EN
dc.identifier.doi10.3390/ijms18051003


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