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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/48510

Title: Association between Vitamin Intake during Pregnancy and Risk of Small for Gestational Age
Authors: Salcedo-Bellido, Inmaculada
Martínez-Galiano, Juan Miguel
Olmedo-Requena, Rocío
Mozas Moreno, Juan
Bueno-Cavanillas, Aurora
Jiménez-Moleón, José
Delgado Rodríguez, Miguel
Issue Date: 23-Nov-2017
Abstract: Pregnancy increases the requirements of certain nutrients, such as vitamins, to provide nutrition for the newborn. The aim was to analyze the association between dietary intake of vitamins during pregnancy and risk of having a small for gestational age (SGA) newborn. A matched case-control study was conducted (518 cases and 518 controls of pregnant women) in Spain. Dietary vitamin intake during pregnancy was assessed using a validated food frequency questionnaire, categorized into quintiles. Odds ratios (ORs) and their 95% confidence intervals (CI) were estimated with conditional regression logistic models. A protective association was observed between maternal dietary intake of vitamins A and D and SGA. For vitamin B3 and B6, the observed protective effect was maintained after adjusting for potential confounding factors. For vitamin B9, we found only an effect in quintiles 3 and 4 (OR = 0.64; 95% CI, 0.41–1.00; OR = 0.58; 95% CI, 0.37–0.91). Protective effect for vitamin B12 was observed in 4th and 5th quintiles (OR = 0.61; 95% CI, 0.39–0.95; OR = 0.68; 95% CI, 0.43–1.04). No associations were detected between dietary intake of vitamins B2, E and C intake and SGA. Our results suggest a positive association between dietary vitamin intake during pregnancy and the weight of the newborn, although more studies are necessary and there could be a ceiling effect for higher intakes of some vitamins cannot be discarded.
Sponsorship: This work was supported by a grant from the National Institute of Health Carlos III (PI11/02199).
Publisher: MDPI
Keywords: Maternal nutrition
Dietary vitamins intake
Small for gestational age
URI: http://hdl.handle.net/10481/48510
ISSN: 2072-6643
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Salcedo-Bellido, I.; et al. Association between Vitamin Intake during Pregnancy and Risk of Small for Gestational Age. Nutrients, 9(12): 1277 (2017). [http://hdl.handle.net/10481/48510]
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