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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/44409

Title: Hospital effluent constitutes a source of vancomycin-resistant enterococci
Other Titles: El efluente hospitalario como fuente de enterococos vancomicina resistentes
Authors: Nuñez, Lidia
Tornello, Carina
Puentes, Noel
Espigares Rodríguez, Elena
Moreno Roldán, Elena
Espigares García, Miguel
Moretton, Juan
Issue Date: 2016
Abstract: Objetivos: Las especies de enterococos son intrínsecamente resistentes a varios antibióticos, adquieren resistencia con relativa facilidad, y difunden estos genes de resistencia a otras especies. La resistencia a los antibióticos en enterococos está asociada al uso de los mismos en la clínica médica y también a la diseminación de clones resistentes en el mundo. El objetivo de este trabajo fue comparar las características de las cepas de enterococos resistentes a vancomicina (ERV) aisladas en efluentes hospitalarios y aguas residuales urbanas. Métodos: Se obtuvieron muestras de los efluentes del Hospital Universitario José de San Martín (Buenos Aires) y muestras de aguas residuales urbanas de la ciudad de Buenos Aires. Resultados: Los recuentos de ERV fueron mayores en los efluentes hospitalarios, siendo la odds ratio 36.4 (IC95%: 26.0-50.8; p<0.0001). Los ERV aislados se identificaron principalmente como E. faecium. Los resultados indicaron una alta prevalencia de enterococos resistentes al resto de los antibióticos ensayados. Conclusión: Podemos concluir que los efluentes de los centros hospitalarios constituyen una fuente de enterococos de resistencia múltiple a antibióticos.
Objectives: Enterococci are intrinsically resistant to many commonly used antimicrobial agents. They are able to acquire resistance with relative ease and can spread these genes to other species. Enterococci resistant to antibiotics are associated with the use of these in clinical practice and also the spread of resistant clones in the world. The aim of this work was to compare the characteristics of the strains of vancomycin-resistant enterococci (VRE) isolated from municipal wastewater and hospital effluent. Methods: Samples were obtained from the effluent of the Hospital Universitario José de San Martín (Buenos Aires) and the municipal wastewater of the city of Buenos Aires. Results: The bacterial counts of VRE were greater in the hospital effluent, with an odds ratio of 36.4 (95% CI: 26.0-50.8; p<0.0001). The VRE isolated were mainly identified as E. faecium. The results indicate a high prevalence of enterococci resistant to the antibiotics tested. Conclusion: We may conclude that the effluents of hospitals constitute a source of VRE showing multiple resistance to antibiotics.
Sponsorship: The authors declare that they have no funding
Publisher: Universidad de Granada. Facultad de Farmacia
Description: We would like to acknowledge César Criado Sánchez, Laboratory Technician of the Department of Preventive Medicine and Public Health, Faculty of Pharmacy, University of Granada, Spain, for his invaluable help in making this study possible. We also thank Jean Louise Sanders for translating and editing the manuscript.
Keywords: Enterococos resistentes a vancomicina
Multirresistencia
Efluente hospitalario
Antibióticos
Aguas residuales urbanas
Vancomycin-resistant enterococci
Multi-resistance
Hospital effluent
Antibiotics
Municipal wastewater
URI: http://hdl.handle.net/10481/44409
ISSN: 2340-9894
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Nuñez, L.; et al. Hospital effluent constitutes a source of vancomycin-resistant enterococci. Ars Pharm, 57(3): 121-126 (2016). [http://hdl.handle.net/10481/44409]
Appears in Collections:APh. vol. 57(3)

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