Formas farmacéuticas y microencapsulación para la administración oral de probióticos

Abstract

El presente Trabajo de Investigación tiene como objetivo principal el diseño de técnicas que permitan proteger a los probióticos de agentes externos de manera que se garantice una viabilidad adecuada de los mismos al final del proceso tecnológico y la llegada en número suficiente al intestino.

This thesis has been developed within the Andalusian Research Group CTS-205 “Practical pharmaceutics” in collaboration with NIZO Food Research (Ede, The Netherland). One of the research lines of the group CTS-205 is the development of different dosage forms and particles for the administration of probiotics. Specifically, this thesis has been focused in the preparation and characterization of microparticles for the protection of L. fermentum CECT 5716 and Lactobacillus plantarum WCSF-1. Furthermore, preparation of tablets for the administration of L. fermentum CECT5716 was also performed.