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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/39133

Title: Biologic Agents for Periodontal Regeneration and Implant Site Development
Authors: Suárez-López del Amo, Fernando
Monje, Alberto
Padial-Molina, Miguel
Tang, ZhiHui
Wang, Hom-Lay
Issue Date: 2015
Abstract: The advancement of molecular mediators or biologic agents has increased tremendously during the last decade in periodontology and dental implantology. Implant site development and reconstruction of the lost periodontium represent main fields in which these molecular mediators have been employed and investigated. Different growth factors trigger different reactions in the tissues of the periodontium at various cellular levels. Proliferation, migration, and differentiation constitute the main target areas of these molecular mediators. It was the purpose of this comprehensive review to describe the origin and rationale, evidence, and the most current understanding of the following biologic agents: Recombinant Human Platelet-Derived Growth Factor-BB (rhPDGF-BB), Enamel Matrix Derivate (EMD), Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF), Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2), Bone Morphogenic Proteins (BMPs, BMP-2 and BMP-7), Teriparatide PTH, and Growth Differential Factor-5 (GDF-5).
Sponsorship: This paper was partially supported by the University of Michigan Periodontal Graduate Student Research Fund.
Publisher: Hindawi Publishing Corporation
Keywords: Periodontal
Implant Site
URI: http://hdl.handle.net/10481/39133
ISSN: 2314-6133
Citation: Suárez-López del Amo, F.; et al. Biologic Agents for Periodontal Regeneration and Implant Site Development. Biomed Research International, 2015: 957518 (2015). [http://hdl.handle.net/10481/39133]
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