Universidad de Granada Digibug
 

Repositorio Institucional de la Universidad de Granada >
1.-Investigación >
Departamentos, Grupos de Investigación e Institutos >
Grupo: Biomateriales y salud laboral en odontología (CTS242) >
CTS242 - Artículos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/39011

Title: Polyaspartic acid enhances dentine remineralization bonded with a zinc-doped Portland-based resin cement
Authors: Osorio Ruiz, Raquel
Sauro, Salvatore
Watson, Timothy F.
Toledano Pérez, Manuel
Issue Date: Aug-2015
Abstract: Aim. To ascertain if biomimetic phosphoproteins analogues (polyaspartic acid -PAS- and sodium trimetaphosphate -TMP-) improve bonding efficacy and dentine remineralization ability of a novel zinc-doped Portland-based resinous sealing cement.
Methodology. Bonding procedures were performed on phosphoric acid etched dentine and several groups were established regarding biomimetic analogue application: 1) No application, 2) PAS-treated dentine and 3) dentine treated with a mixture of PAS and TMP. Raman spectroscopy and microtensile bond strength (MTBS) with fracture analysis by scanning electron microscopy were carried out. MTBS values were compared by ANOVA, Student-Newman-Keuls and Student t tests (P<0.05 and P<0.01 respectively).
Results. MTBS values were not affected by the different bonding procedures, at 24 h testing. After 6 months, MTBS decreased in those groups in which analogues phosphoproteins’ were not applied (P<0.05). When Pas was applied, MTBS was maintained after 6 months (P>0.05). The novel material bonded without primers application induced bioactive crystal (calcium carbonate and Ettringite) precipitation onto the etched dentine and augmented the degree of crystallinity at the hybrid layer. Mineral to matrix ratio was increased at the hybrid layer of the PAS-treated specimens; this primer was also able to catalyze dentine remineralization, without an increase in crystallinity.
Conclusions: PAS application onto demineralized dentine produced an inhibition or delay of the mineral phase crystallization, enhancing the remineralization potential of the Portland microfillers at the resin-dentine bonded interface.
Sponsorship: This work was supported by grant MINECO/FEDER MAT2011-24551 and MAT2014-52036-P.
Publisher: John Wiley and Sons
Description: "This is the pre-peer reviewed version of the following article: "Osorio R, Sauro S, Watson TF, Toledano M. Polyaspartic acid enhances dentine remineralization bonded with a zinc-doped Portland-based resin cement. International Endodontic Journal", which has been published in final form at http://dx.doi.org/10.1111/iej.12518. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."
Keywords: Bonding
Dentine
Remineralization
Resin
URI: http://hdl.handle.net/10481/39011
ISSN: 1365-2591
0143-2885
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Osorio, R.; Sauro, S.; Watson, T.F.; Toledano Pérez, M. Polyaspartic acid enhances dentine remineralization bonded with a zinc-doped Portland-based resin cement. International Endodontic Journal, 48: online (2015). [http://hdl.handle.net/10481/39011]
Appears in Collections:CTS242 - Artículos

Files in This Item:

File Description SizeFormat
Osorio_PolyasparticAcid.pdf1.61 MBAdobe PDFView/Open
Recommend this item

This item is licensed under a Creative Commons License
Creative Commons

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! OpenAire compliant DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - Feedback

© Universidad de Granada