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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/37238

Title: Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment
Authors: Henríquez-Hernández, Luis Alberto
Valenciano, Almudena
Foro-Arnalot, Palmira
Álvarez-Cubero, María Jesús
Cózar Olmo, José Manuel
Suárez-Novo, José Francisco
Castells-Esteve, Manel
Fernández-Gonzalo, Pablo
De-Paula-Carranza, Belén
Ferrer, Montse
Guedea, Ferrán
Sancho-Pardo, Gemma
Craven-Bartle, Jordi
Ortiz-Gordillo, María José
Cabrera-Roldán, Patricia
Herrera-Ramos, Estefanía
Rodríguez-Gallego, Carlos
Lara, Pedro C.
Issue Date: 2015
Abstract: We designed a study aimed to evaluate the genotypic distribution of 22 SNPs in SRD5A1 and SRD5A2 in a set of Spanish prostate cancer patients, to determine the homogeneity of the population and to disclose potential bias associated with the failure of 5α-RI when prescribed.
Sponsorship: This work was subsidized by the grant from the Instituto de Salud Carlos III (Ministerio de Economía y Competitividad from Spain), ID: PI12/01867. Almudena Valenciano has a grant from the Instituto Canario de Investigación del Cáncer (ICIC).
Publisher: Indian Academy of Sciences
Keywords: 5-alpha-reductase polymorphism
5-alpha-reductase inhibitors
OpenArray
Prostate cancer
Pharmacoethnicity
URI: http://hdl.handle.net/10481/37238
ISSN: 0022-1333
Citation: Henríquez-Hernández, L.A.; et al. Intraethnic variation in steroid-5-alpha-reductase polymorphisms in prostate cancer patients: a potential factor implicated in 5-alpha-reductase inhibitor treatment. Journal of Genetics, 94(2): 335-341 (2015). [http://hdl.handle.net/10481/37238]
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