Universidad de Granada Digibug

Repositorio Institucional de la Universidad de Granada >
1.-Investigación >
Departamentos, Grupos de Investigación e Institutos >
Departamento de Estomatología >
DE - Artículos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/35850

Title: Oral and general health-related quality of life in patients treated for oral cancer compared to control group
Authors: Barrios Rodríguez, Rocío
Bravo Pérez, Manuel
Gil Montoya, José Antonio
Martínez Lara, Ildefonso
García Medina, Blas
Tsakos, Georgios
Issue Date: 2015
Abstract: Background: Health-related quality of life (HRQoL) is gaining importance as a valuable outcome measure in oral cancer area. The aim of this study was to assess the general and oral HRQoL of oral and oropharyngeal cancer patients 6 or more months after treatment and compare them with a population free from this disease.
Methods: A cross-sectional study was carried out with patients treated for oral cancer at least 6 months post-treatment and a gender and age group matched control group. HRQoL was measured with the 12-Item Short Form Health Survey (SF-12); oral HRQoL (OHRQoL) was evaluated using the Oral Health Impact Profile (OHIP-14) and the Oral Impacts on Daily Performances (OIDP). Multivariable regression models assessed the association between the outcomes (SF-12, OHIP-14 and OIDP) and the exposure (patients versus controls), adjusting for sex, age, social class, functional tooth units and presence of illness.
Results: For patients (n = 142) and controls (n = 142), 64.1% were males. The mean age was 65.2 (standard deviation (sd): 12.9) years in patients and 67.5 (sd: 13.7) years in controls. Patients had worse SF-12 Physical Component Summary scores than controls even in fully the adjusted model [β-coefficient = −0.11 (95% CI: −5.12-(−0.16)]. The differences in SF-12 Mental Component Summary were not statistically significant. Regarding OHRQoL patients had 11.63 (95% CI: 6.77-20.01) higher odds for the OHIP-14 and 21.26 (95% CI: 11.54-39.13) higher odds for OIDP of being in a worse category of OHRQoL compared to controls in the fully adjusted model.
Conclusion: At least 6 months after treatment, oral cancer patients had worse OHRQoL, worse physical HRQoL and similar psychological HRQoL than the general population.
Sponsorship: Rocio Barrios, academic training, is being supported by the postgraduate research fellowship “Programa de Formación del Profesorado Universitario” from the Spanish Ministry of Education, Culture and Sport. This study was also supported by the Andalusian Research Group CTS-503.
Publisher: Biomed Central
Keywords: Oral cancer
Quality of life
URI: http://hdl.handle.net/10481/35850
ISSN: 1477-7525
Citation: Barrios, R.; et al. Oral and general health-related quality of life in patients treated for oral cancer compared to control group. Health and Quality of Life Outcomes, 13: 9 (2015). [http://hdl.handle.net/10481/35850]
Appears in Collections:DE - Artículos

Files in This Item:

File Description SizeFormat
Barrios_OralCancer.pdf363.76 kBAdobe PDFView/Open
Recommend this item

This item is licensed under a Creative Commons License
Creative Commons

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! OpenAire compliant DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - Feedback

© Universidad de Granada