Mostrar el registro sencillo del ítem
Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study
dc.contributor.author | Gutiérrez-Fernández, José | |
dc.contributor.author | Luna Del Castillo, Juan De Dios | |
dc.contributor.author | Mañanes-González, Sara | |
dc.contributor.author | Carrillo-Ávila, José Antonio | |
dc.contributor.author | Gutiérrez, Blanca | |
dc.contributor.author | Cervilla, Jorge A. | |
dc.contributor.author | Sorlozano Puerto, Antonio | |
dc.date.accessioned | 2015-04-17T10:56:23Z | |
dc.date.available | 2015-04-17T10:56:23Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Gutiérrez-Fernández, J.; et al. Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study. Neuropsychiatric Disease and Treatment, 11: 843-852 (2015). [http://hdl.handle.net/10481/35709] | es_ES |
dc.identifier.issn | 1178-2021 | |
dc.identifier.uri | http://hdl.handle.net/10481/35709 | |
dc.description.abstract | In the present study we have performed both a meta-analysis and an analytical study exploring the presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii antibodies in a sample of 143 schizophrenic patients and 143 control subjects. The meta-analysis was performed on papers published up to April 2014. The presence of serum immunoglobulin G and immunoglobulin A was performed by enzyme-linked immunosorbent assay test. The detection of microbial DNA in total peripheral blood was performed by nested polymerase chain reaction. The meta-analysis showed that: 1) C. pneumoniae DNA in blood and brain are more common in schizophrenic patients; 2) there is association with parasitism by T. gondii, despite the existence of publication bias; and 3) herpes viruses were not more common in schizophrenic patients. In our sample only anti-Toxoplasma immunoglobulin G was more prevalent and may be a risk factor related to schizophrenia, with potential value for prevention. | es_ES |
dc.description.sponsorship | Part of this work was presented at the Royal Academy of Medicine of Spain. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Dove Press | es_ES |
dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | |
dc.subject | Meta-analysis | es_ES |
dc.subject | Analytical study | es_ES |
dc.subject | Chlamydia pneumoniae | es_ES |
dc.subject | Herpes simplex virus type 1 | es_ES |
dc.subject | Human herpes virus 6 | es_ES |
dc.subject | Toxoplasma gondii | es_ES |
dc.subject | Schizophrenia | es_ES |
dc.title | Different presence of Chlamydia pneumoniae, herpes simplex virus type 1, human herpes virus 6, and Toxoplasma gondii in schizophrenia: meta-analysis and analytical study | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.2147/NDT.S79285 |