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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/34955

Title: SWI/SNF proteins as targets in cancer therapy
Authors: Schiaffino-Ortega, Santiago
Balinas, Carlos
Cuadros Celorrio, Marta
Medina Vico, Pedro
Issue Date: 2014
Abstract: Recent identification of synthetic lethal interactions involving several proteins of the SWI/SNF complex discussed in this Research Highlight has opened the possibility of new cancer therapeutic approaches.
Sponsorship: P.P.M. laboratory is funded by Ministry of Economy of Spain (SAF-2012- 37252), Junta de Andalucía (CICE-FEDER-BIO-1655, PeS-FEDER-PI-0903-2012), EU-MarieCurie (CIG-321926), CEI-BIOTIC (20 F12.6), Deutsche Leukämie-Stiftung and BBVA Foundation. P.P.M is a Ramon y Cajal Researcher (RYC-2011-07766). S S-O has a postdoctoral fellowship of Junta de Andalucía (CTS 03210) and the support of the CEI-BIOTIC (2014-MPBS33).
Publisher: Biomed Central
Keywords: SWI/SNF complex
Cancer therapy
Epigenetic
Tumor suppressor
Synthetic lethality
Leukemia
Lung cancer
BRG1
SMARCA4
BRM
SMARCA2
MAX
MYC
URI: http://hdl.handle.net/10481/34955
ISSN: 1756-8722
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Schiaffino-Ortega, S.; et al. SWI/SNF proteins as targets in cancer therapy. Journal of Hematology and Oncology, 7: 81 (2014). [http://hdl.handle.net/10481/34955]
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