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dc.contributor.authorRuiz-Linares, Matildees_ES
dc.contributor.authorFerrer Luque, Carmen María es_ES
dc.contributor.authorArias-Moliz, Teresaes_ES
dc.contributor.authorCastro, Paula dees_ES
dc.contributor.authorAguado Pérez, Beatrizes_ES
dc.contributor.authorBaca García, Pilares_ES
dc.date.accessioned2014-10-17T09:29:00Z
dc.date.available2014-10-17T09:29:00Z
dc.date.issued2014
dc.identifier.citationRuiz-Linares, M.; et al. Antimicrobial activity of alexidine, chlorhexidine and cetrimide against Streptococcus mutans biofilm. Annals of Clinical Microbiology and Antimicrobials, 13: 41 (2014). [http://hdl.handle.net/10481/33429]es_ES
dc.identifier.issn1476-0711
dc.identifier.urihttp://hdl.handle.net/10481/33429
dc.description.abstractBackground The use of antimicrobial solutions has been recommended to disinfect demineralized dentin prior to placing the filling material. The aim of this study was to evaluate the ability of several antimicrobials in controlling Streptococcus mutans (SM) biofilm formed in dentin. Methods Antimicrobial activity of 0.2% and 2% chlorhexidine (CHX), 0.2% cetrimide (CTR) and 0.2%, 0.5%, 1% and 2% alexidine (ALX) was assayed on 1-week SM biofilm formed on standardized coronal dentin blocks. Results of SM biofilm antimicrobial activity by different protocols were expressed as the kill percentage of biofilm and the term “eradication” was used to denote the kill of 100% of the bacterial population. To compare the efficacies of the different protocols the Student t test was used, previously subjecting data to the Anscombe transformation. Results All ALX concentrations tested and 0.2% CTR achieved a kill percentage higher than 99%, followed by 2% CHX with percentages above 96% (no statistically significant difference among them). Whereas 2% ALX and 0.2% CTR respectively showed eradication in 10 and 9 of the twelve specimens, 0.2% CHX did not produce eradication in any case. Conclusions The present study shows that, when used for one minute, 2% and 1% alexidine, and 0.2% cetrimide, achieve eradication of Streptococcus mutans biofilm in most specimens when applied to a dentin-volumetric model.es_ES
dc.description.sponsorshipThis study was supported by Research Group CTS-167 of the Junta de Andalucía, Spain.es_ES
dc.language.isoenges_ES
dc.publisherBiomed Centrales_ES
dc.subjectAlexidinees_ES
dc.subjectBiofilmes_ES
dc.subjectCetrimidees_ES
dc.subjectChlorhexidinees_ES
dc.subjectStreptococcus mutanses_ES
dc.titleAntimicrobial activity of alexidine, chlorhexidine and cetrimide against Streptococcus mutans biofilmes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1186/s12941-014-0041-5


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