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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/32816

Title: Factors associated with improvement in disability-adjusted life years in patients with HIV/AIDS
Authors: Bermúdez-Tamayo, Clara
Martín-Martín, José Jesús
Ruiz-Pérez, Isabel
Olry de Labry Lima, Antonio
Issue Date: 2008
Abstract: Background: The epidemic of HIV/AIDS and treatments that have emerged to alleviate, have brought about a shift in the burden of disease from death to quality of life/disability. The aim was to determine which factors are associated with improvements in the level of health of male and female patients with HIV/AIDS in Andalusia, in terms of disability-adjusted life years. Methods: Descriptive study based on a sample group of 8800 people on the Andalusian AIDS register between 1983 and 2004. Dependent variables: Life lost due to premature mortality (YLL), years lost due to disability (YLD) and disability-adjusted life years (DALY). Independent variables: vital state, sex, age at the time of diagnosis, age at the time of death, transmission category, province of residence, AIDS-indicator disease and the period of diagnosis. A bivariate analysis was carried out to find out if the health level variables changed in accordance with the independent variables. Using the independent variables which had a statistically significant link with the level of health variables, a multivariate linear regression model, disaggregated by gender, was constructed. Results: Amongst the women, we found a model which explained the level of health of 64.9%: a link was found between a higher level of health (lower DALYs) and not intravenous drug use, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis. Amongst the men, we found a model which explained the level of health of 64.4%: a link was found between a higher level of health (lower DALYs) and intravenous drug use, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis. Conclusion: A higher level of health (lower DALY) amongst both men and women was found to be linked to not be intravenous drug user, the province of residence, being diagnosed during the HAART era and older age at the time of diagnosis.
Publisher: Biomed Central
Keywords: Combination antiretroviral therapy
HIV
Cost-effectiveness
Haart
SIDA / VIH
URI: http://hdl.handle.net/10481/32816
ISSN: 1471-2458
Citation: Bermúdez-Tamayo, C.; et al. Factors associated with improvement in disability-adjusted life years in patients with HIV/AIDS. BMC Public Health, 8: 362 (2008). [http://hdl.handle.net/10481/32816]
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