Universidad de Granada Digibug
 

Repositorio Institucional de la Universidad de Granada >
1.-Investigación >
Departamentos, Grupos de Investigación e Institutos >
Departamento de Fisiología >
DFisiología - Artículos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/32397

Title: Effect of folic acid supplementation on homocysteine concentration and association with training in handball players
Authors: Molina-López, Jorge
Molina-Molina, José-Manuel
Chirosa Ríos, Luis Javier
Florea, Daniela Ioana
Sáez, Laura
Planells del Pozo, Elena María
Issue Date: 2013
Abstract: [Background] Strenuous physical activity can alter the status of folic acid, a vitamin directly associated with homocysteine (Hcy); alterations in this nutrient are a risk factor for cardiovascular disease. Handball players are a population at risk for nutrient deficiency because of poor dietary habits. [Objective] The aims of this study were to evaluate nutritional status for macronutrients and folic acid in members of a high-performance handball team, and determine the effect of a nutritional intervention with folic acid supplementation and education. [Design] A total of 14 high-performance handball players were monitored by recording training time, training intensity (according to three levels of residual heart rate (RHR): <60%, 60%–80% and >80%), and subjective perceived exertion (RPE) during a 4-month training period. Nutritional, laboratory and physical activity variables were recorded at baseline (Week 0), after 2 months of dietary supplementation with 200 μg folic acid (50% of the recommended daily allowance) (Week 8) and after 2 months without supplementation (Week 16). We compared training load and analyzed changes in plasma concentrations of Hcy before and after the intervention. [Results] Bivariate analysis showed a significant negative correlation (P < 0.01) between Hcy and folic acid concentrations (r = −0.84) at Week 8, reflecting a significant change in Hcy concentration (P < 0.05) as a result of hyperhomocysteinemia following the accumulation of high training loads. At Week 16 we observed a significant negative correlation (P < 0.01) between Hcy concentration and training time with an RHR <60%, indicating that aerobic exercise avoided abrupt changes in Hcy and may thus reduce the risk of cardiovascular accidents in high-performance athletes. [Conclusion] Integral monitoring and education are needed for practitioners of handball sports to record their folic acid status, a factor that directly affects Hcy metabolism. Folic acid supplementation may protect athletes against alterations that can lead to cardiovascular events related to exertion during competition.
Sponsorship: This work was supported by the Spanish Ministry of Education (grant number AP2009- 3701) and by FIS Project PI07/1228 form the Carlos III Health Institute.
Publisher: Biomed Central
Keywords: Nutritional status
Sport
Folic acid
Supplementation
Homocysteine
URI: http://hdl.handle.net/10481/32397
ISSN: 1550-2783
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Molina-López, J.; et al. Effect of folic acid supplementation on homocysteine concentration and association with training in handball players. Journal of the International Society of Sports Nutrition, 10: 10 (2013). [http://hdl.handle.net/10481/32397]
Appears in Collections:DFisiología - Artículos

Files in This Item:

File Description SizeFormat
MolinaLopez_HandballPlayers.pdf310.3 kBAdobe PDFView/Open
Recommend this item

This item is licensed under a Creative Commons License
Creative Commons

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! OpenAire compliant DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - Feedback

© Universidad de Granada