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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/32396

Title: Ergogenic effects of quercetin supplementation in trained rats
Authors: Casuso, Rafael A.
Martínez-Amat, Antonio
Martínez-López, Emilio José
Camiletti-Moirón, Daniel
Porres-Foulquie, Jesús
Aranda Ramírez, Pilar
Issue Date: 2013
Abstract: [Background] Quercetin is a natural polyphenolic compound currently under study for its ergogenic capacity to improve mitochondrial biogenesis. Sedentary mice have exhibited increased endurance performance, but results are contradictory in human models. [Methods] We examined the effects of six weeks of endurance training and quercetin supplementation on markers of endurance performance and training in a rodent model. Rats were randomly assigned to one of the following groups: placebo+sedentary (PS), quercetin+sedentary (QS), placebo+endurance training (PT) and quercetin+endurance training (QT). Quercetin was administered at a dose of 25 mg/kg on alternate days. During six weeks of treatment volume parameters of training were recorded, and after six weeks all groups performed a maximal graded VO2 max test and a low-intensity endurance run-to-fatigue test. [Results] No effects were found in VO2 peak (p>0.999), nor in distance run during low-intensity test, although it was 14% greater in QT when compared with PT (P = 0.097). Post-exercise blood lactate was increased in QT when compared with PT (p=0.023) and also in QS compared with PS (p=0.024). [Conclusions] This study showed no effects in VO2 peak, speed at VO2 peak or endurance time to exhaustion after six weeks of quercetin supplementation compared with placebo in trained rats. Quercetin was show to increase blood lactate production after high-intensity exercise.
Publisher: Biomed Central
Keywords: Muscle mitochondrial biogenesis
Endurance performance
Exercise performance
Oxygen uptake
Hypertrophy
Antagonists
URI: http://hdl.handle.net/10481/32396
ISSN: 1550-2783
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Casuso, R.A.; et al. Ergogenic effects of quercetin supplementation in trained rats. Journal of the International Society of Sports Nutritions, 10: 3 (2013). [http://hdl.handle.net/10481/32396]
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