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dc.contributor.authorLópez-Céspedes, Ángeles
dc.contributor.authorVillagrán-Herrera, Elena
dc.contributor.authorBriceño Álvarez, Kervin
dc.contributor.authorDiego-Cabrera, José Antonio de
dc.contributor.authorHernández-Montiel, Hebert Luis
dc.contributor.authorSaldaña, Carlos
dc.contributor.authorSánchez Moreno, Manuel 
dc.contributor.authorMarín Sánchez, Clotilde 
dc.date.accessioned2014-05-30T08:26:48Z
dc.date.available2014-05-30T08:26:48Z
dc.date.issued2012
dc.identifier.citationLópez-Céspedes, A.; et al. Trypanosoma cruzi: seroprevalence detection in suburban population of Santiago de Querétaro (Mexico). Scientific World Journal, 2012: 914129 (2012). [http://hdl.handle.net/10481/32043]es_ES
dc.identifier.issn1537-744X
dc.identifier.urihttp://hdl.handle.net/10481/32043
dc.description.abstractObjectives. To evaluate the potential of iron-oxide dismutase excreted (SODeCRU) by T. cruzi as the antigen fraction in the serodiagnosis of Chagas disease and compile new epidemiological data on the seroprevalence of this disease in the suburban population of the city of Santiago de Querétaro (Mexico). Design and Methods. 258 human sera were analyzed by the techniques of ELISA and Western blot and using the homogenate and the SODeCRU. Results. A total of 31 sera were positive against ELISA/SODeCRU (12.4%), while 30 sera proved positive by WB/SODeCRU (11.6%). The comparison between the technique of ELISA and WB showed a sensitivity of 93%, and a specificity of 99%. The positive predictive value was 93% and the negative predictive value was 99%, with a Kappa (κ) value of 1. Conclusions. These preliminary data reveal the degree of infection of nonrural areas of Mexico and demonstrated that SODeCRU is an antigen useful to diagnose Chagas disease.es_ES
dc.description.sponsorshipThis work was supported by the University of Granada (Program GREIB, GREIB.PYR_2011_18).es_ES
dc.language.isoenges_ES
dc.publisherHindawi Publishing Corporationes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es_ES
dc.subjectPolymerase chain reactiones_ES
dc.subjectSuperoxide dismutasees_ES
dc.subjectChagas diseasees_ES
dc.subjectCutaneous leishmaniasises_ES
dc.subjectInfection es_ES
dc.subjectTestses_ES
dc.subjectDogs es_ES
dc.titleTrypanosoma cruzi: seroprevalence detection in suburban population of Santiago de Querétaro (Mexico)es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1100/2012/914129


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