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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/31356

Title: Association of 25-hydroxyvitamin D with Metabolic Syndrome in Patients with Psoriasis: A Case-control Study
Authors: Orgaz Molina, Jacinto
Magro-Checa, César
Arrabal-Polo, Miguel Ángel
Raya-Álvarez, Enrique
Naranjo Sintes, Ramón José
Buendía Eisman, Agustín
Arias-Santiago, Salvador
Issue Date: 2014
Abstract: Vitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 control subjects, matched by sex and age. The patients with psoriasis showed significantly lower level of 25-OHD than controls (30.5 vs. 38.3 ng/ml; p =0.0001). Patients with MeS had significantly lower serum levels of 25-OHD than those without MeS (24.1 +/- 7.5 vs. 32.8 +/- 8.9,p =0.007), and a negative correlation was found between 25-OHD and waist circumference, diastolic blood pressure, fasting glucose, and triglyceridaemia. In the control group no significant correlation between 25-OHD and MeS was found. Although the sample was small, our results suggest a potential protective role for 25-OHD in the metabolic profile of patients with psoriasis without arthritis.
Publisher: Society for the Publication of Acta Dermato - Venereologica
Keywords: Psoriasis
Vitamin D
Metabolic syndrome
Cardiovascular risk
URI: http://hdl.handle.net/10481/31356
ISSN: 0001-5555
1651-2057
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Orgaz-Molina, J.; et al. Association of 25-hydroxyvitamin D with Metabolic Syndrome in Patients with Psoriasis: A Case-control Study. Acta Demato-Venereologica, 94: 142-145 (2014). [http://hdl.handle.net/10481/31356]
Appears in Collections:DDer - Artículos

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