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Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/29649

Title: Vinyl sulfone: a multi-purpose function in proteomics
Authors: López Jaramillo, Francisco Javier
Hernández Mateo, Fernando
Santoyo González, Francisco
Issue Date: 2012
Abstract: The chapter is organized in three sections. In a first instance, a general overview of the vinyl sulfone chemistry in terms of the most relevant methods of synthesis and aspects of their reactivity will be followed by a discussion of the application of this chemical behaviour with proteins. Their advantages and disadvantages with other currently available methodologies to modify amine and thiol groups naturally present in proteins will be compared. In a second section the applications of vinyl sulfones to Proteomics will be enumerated. Finally, the wide scope of the vinyl sulfone chemistry in other omic sciences will be discussed.
Sponsorship: The authors acknowledge Dirección General de Investigación Científica y Técnica (DGICYT) (CTQ2008-01754) and Junta de Andalucía (P07-FQM-02899) for financial support.
Publisher: Intech
Keywords: Vinyl sulfone
Proteomics
Chemistry
Synthesis
URI: http://hdl.handle.net/10481/29649
ISBN: 978-953-51-0070-6
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: López Jaramillo, F.J.; Hernández Mateo, F.; Santoyo González, F. Vinyl sulfone: a multi-purpose function in proteomics. In: Eastwood Leung, H.-C. (ed.), Integrative proteomics. Rijeka (Croatia): Intech, 2012. pp. 301- 326. [http://hdl.handle.net/10481/29649]
Appears in Collections:DQO - Capítulos de libros

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