Universidad de Granada Digibug
 

Repositorio Institucional de la Universidad de Granada >
1.-Investigación >
Departamentos, Grupos de Investigación e Institutos >
Grupo: Evaluación Funcional y Fisiología del Ejercicio (CTS262) >
EFFE CTS-262 - Artículos >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10481/28995

Title: Muscular strength in male adolescents and premature death: cohort study of one million participants
Authors: Ortega Porcel, Francisco B.
Silventoinen, K.
Tynelius, P.
Rasmussen, F.
Issue Date: 2012
Abstract: Objectives To explore the extent to which muscular strength in adolescence is associated with all cause and cause specific premature mortality (<55 years). Design Prospective cohort study. Setting Sweden. Participants 1 142 599 Swedish male adolescents aged 16-19 years were followed over a period of 24 years. Main outcome measures Baseline examinations included knee extension, handgrip, and elbow flexion strength tests, as well as measures of diastolic and systolic blood pressure and body mass index. Cox regression was used to estimate hazard ratios for mortality according to muscular strength categories (tenths). Results During a median follow-up period of 24 years, 26 145 participants died. Suicide was a more frequent cause of death in young adulthood (22.3%) than was cardiovascular diseases (7.8%) or cancer (14.9%). High muscular strength in adolescence, as assessed by knee extension and handgrip tests, was associated with a 20-35% lower risk of premature mortality due to any cause or cardiovascular disease, independently of body mass index or blood pressure; no association was observed with mortality due to cancer. Stronger adolescents had a 20-30% lower risk of death from suicide and were 15-65% less likely to have any psychiatric diagnosis (such as schizophrenia and mood disorders). Adolescents in the lowest tenth of muscular strength showed by far the highest risk of mortality for different causes. All cause mortality rates (per 100 000 person years) ranged between 122.3 and 86.9 for the weakest and strongest adolescents; corresponding figures were 9.5 and 5.6 for mortality due to cardiovascular diseases and 24.6 and 16.9 for mortality due to suicide. Conclusions Low muscular strength in adolescents is an emerging risk factor for major causes of death in young adulthood, such as suicide and cardiovascular diseases. The effect size observed for all cause mortality was equivalent to that for well established risk factors such as elevated body mass index or blood pressure.
Sponsorship: The study was supported by a grant to FR from the Swedish Research Council (grant 2007-5942). FBO was supported by grants from the Spanish Ministry of Science and Innovation (RYC-2011-09011).
Publisher: BMJ
Keywords: Epidemiologic studies
Hypertension
Child and adolescent psychiatry
Cardiovascular system
Suicide
Mood disorders
Psychotic disorders
URI: http://hdl.handle.net/10481/28995
ISSN: 0959-8138
1756-1833
Rights : Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License
Citation: Ortega, F.B.; et al. Muscular strength in male adolescents and premature death: cohort study of one million participants. BMJ, 345: e7279 (2012). [http://hdl.handle.net/10481/28995]
Appears in Collections:EFFE CTS-262 - Artículos

Files in This Item:

File Description SizeFormat
Ortega_MuscularStrength.pdf1.34 MBAdobe PDFView/Open
Recommend this item

This item is licensed under a Creative Commons License
Creative Commons

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! OpenAire compliant DSpace Software Copyright © 2002-2007 MIT and Hewlett-Packard - Feedback

© Universidad de Granada