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dc.contributor.authorFerrari, M.
dc.contributor.authorMistura, L.
dc.contributor.authorPatterson, E.
dc.contributor.authorSjöström, Michael
dc.contributor.authorDíaz, L. E.
dc.contributor.authorStehle, P.
dc.contributor.authorGonzález Gross, Marcela
dc.contributor.authorKersting, Mathilde
dc.contributor.authorWidhalm, Kurt
dc.contributor.authorMolnar, Dénes
dc.contributor.authorGottrand, Frederic
dc.contributor.authorHenauw, Stefaan de
dc.contributor.authorManios, Yannis
dc.contributor.authorKafatos, A.
dc.contributor.authorMoreno, L. A.
dc.contributor.authorLeclercq, C.
dc.date.accessioned2013-10-29T10:14:03Z
dc.date.available2013-10-29T10:14:03Z
dc.date.issued2011
dc.identifier.citationFerrari, M.; et al. Evaluation of iron status in European adolescents through biochemical iron indicators: the HELENA Study. European Journal of Clinical Nutrition, 65(3): 340-349 (2011). [http://hdl.handle.net/10481/28879]es_ES
dc.identifier.issn1476-5640
dc.identifier.issn0954-3007
dc.identifier.urihttp://hdl.handle.net/10481/28879
dc.description.abstractBackground/Objectives: To assess the iron status among European adolescents through selected biochemical parameters in a cross-sectional study performed in 10 European cities. Subjects/Methods: Iron status was defined utilising biochemical indicators. Iron depletion was defined as low serum ferritin (SF<15 μg/l). Iron deficiency (ID) was defined as high-soluble transferrin receptor (sTfR>8.5 mg/l) plus iron depletion. Iron deficiency anaemia (IDA) was defined as ID with haemoglobin (Hb) below the WHO cutoff for age and sex: 12.0 g/dl for girls and for boys aged 12.5–14.99 years and 13.0 g/dl for boys aged greater than or equal to15 years. Enzyme linked immunosorbent assay was used as analytical method for SF, sTfR and C-reactive protein (CRP). Subjects with indication of inflammation (CRP >5 mg/l) were excluded from the analyses. A total of 940 adolescents aged 12.5–17.49 years (438 boys and 502 girls) were involved. Results: The percentage of iron depletion was 17.6%, significantly higher in girls (21.0%) compared with boys (13.8%). The overall percentage of ID and IDA was 4.7 and 1.3%, respectively, with no significant differences between boys and girls. A correlation was observed between log (SF) and Hb (r=0.36, P<0.01), and between log (sTfR) and mean corpuscular haemoglobin (r=−0.30, P<0.01). Iron body stores were estimated on the basis of log (sTfR/SF). A higher percentage of negative values of body iron was recorded in girls (16.5%) with respect to boys (8.3%), and body iron values tended to increase with age in boys, whereas the values remained stable in girls. Conclusions: To ensure adequate iron stores, specific attention should be given to girls at European level to ensure that their dietary intake of iron is adequate.es_ES
dc.description.sponsorshipThe HELENA Study was supported financially by the European Community Sixth RTD Framework Programme (Contract FOOD-CT-2005-007034).es_ES
dc.language.isoenges_ES
dc.publisherNature Publishing Groupes_ES
dc.rightsCreative Commons Attribution-NonCommercial-NoDerivs 3.0 Licensees_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es_ES
dc.subjectAnaemiaes_ES
dc.subjectIron deficiencyes_ES
dc.subjectAdolescentes_ES
dc.subjectEuropees_ES
dc.titleEvaluation of iron status in European adolescents through biochemical iron indicators: the HELENA Studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1038/ejcn.2010.279es_ES


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