@misc{10481/85015,
year = {2023},
month = {8},
url = {https://hdl.handle.net/10481/85015},
abstract = {Introduction: A growing number of studies link the increase in overweight/
obesity worldwide to exposure to certain environmental chemical pollutants that
display obesogenic activity (obesogens). Since exposure to obesogens during
the first stages of life has been shown to have a more intense and pronounced
effect at lower doses, it is imperative to study their possible effects in childhood.
The objective here was to study the association of Bisphenol A (BPA) and 11 BPA
analogs in children, using three biological matrices (nails, saliva and urine), and
overweight and obesity (n = 160).
Methods: In this case–control study, 59 overweight/obese children and 101
controls were included. The measuring of Bisphenols in the matrices was carried
out by ultra-high performance liquid chromatography coupled with triple
quadrupole tandem mass spectrometry (UHPLC-MS/MS). Logistic regression
was used to study the association between overweight/obesity and Bisphenol
exposure.
Results: The results suggested that BPF in nails is associated with overweight/
obesity in children (OR:4.87; p = 0.020). In saliva, however, the highest detected
concentrations of BPAF presented an inverse association (OR: 0.06; p = 0.010)
with overweight/obesity. No associations of statistical significance were detected
between exposure to BPA or its other analogs and overweight/obesity in any of
the biological matrices.},
organization = {FEDER-Consejería de Salud y Familias’ of the Junta de Andalucía PE-0250-2019},
publisher = {Frontiers},
keywords = {Overweight and obesity},
keywords = {Childhood obesity},
keywords = {Obesogens},
keywords = {BPA and analogs},
keywords = {Biological samples},
title = {Levels of Bisphenol A and its analogs in nails, saliva, and urine of children: a case control study},
doi = {10.3389/fnut.2023.1226820},
author = {Gálvez Ontiveros, Yolanda and Moscoso Ruiz, Inmaculada and Almazán Fernández de Bobadilla, Laura and Monteagudo Sánchez, Celia and Rodrigo Conde Salazar, Lourdes T. and Zafra Gómez, Alberto and Rivas Velasco, Ana María},
}