@misc{10481/34955, year = {2014}, url = {http://hdl.handle.net/10481/34955}, abstract = {Recent identification of synthetic lethal interactions involving several proteins of the SWI/SNF complex discussed in this Research Highlight has opened the possibility of new cancer therapeutic approaches.}, organization = {P.P.M. laboratory is funded by Ministry of Economy of Spain (SAF-2012- 37252), Junta de Andalucía (CICE-FEDER-BIO-1655, PeS-FEDER-PI-0903-2012), EU-MarieCurie (CIG-321926), CEI-BIOTIC (20 F12.6), Deutsche Leukämie-Stiftung and BBVA Foundation. P.P.M is a Ramon y Cajal Researcher (RYC-2011-07766). S S-O has a postdoctoral fellowship of Junta de Andalucía (CTS 03210) and the support of the CEI-BIOTIC (2014-MPBS33).}, publisher = {Biomed Central}, keywords = {SWI/SNF complex}, keywords = {Cancer therapy}, keywords = {Epigenetic}, keywords = {Tumor suppressor}, keywords = {Synthetic lethality}, keywords = {Leukemia}, keywords = {Lung cancer}, keywords = {BRG1}, keywords = {SMARCA4}, keywords = {BRM}, keywords = {SMARCA2}, keywords = {MAX}, keywords = {MYC}, title = {SWI/SNF proteins as targets in cancer therapy}, doi = {10.1186/s13045-014-0081-5}, author = {Schiaffino-Ortega, Santiago and Balinas, Carlos and Cuadros Celorrio, Marta Eugenia and Medina Vico, Pedro Pablo}, }